Lahore—Talking over the hum of a power generator, Monis Rahman settles into a plush black chair in a glass-paneled conference room at his offices in Lahore, Pakistan. The midday sun peeks through vertical blinds behind him. Though the power is out yet again, the 40-something tech entrepreneur who runs Naseeb Networks, the job site Rozee.pk, and matchmaking platform Naseeb.com, is unfazed. He’s energized about an upcoming event in his country called TiECon, a conference hosted by the Indus Entrepreneurs Network. “We’re promoting entrepreneurship in a major way,” Rahman says in near-perfect English.

Back in the 1990s, Rahman was working at Intel where his team developed the revolutionary Itanium 64-bit microprocessor chip, the device that acts as a computer’s nervous system, routing information and allowing multitasking. “It was my dream job,” he says.

His family considered it a godsend. Rahman’s father, a...

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