This article revisits Susan Stryker's 2006 introduction to The Transgender Studies Reader to show how her overview of Foucault's “insurrection of subjugated knowledges” in this field-inaugurating text mutes the radical potential of Foucault's genealogical approach to history. Through a close reading of Foucault's original presentation of this concept in his 1976 lecture, the fuller sense of his “antiscience” genealogy becomes clear. The article concludes by proposing a way scholars might redeploy Foucault's insurrectionary method within the field of trans* studies today.

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