To organize and manage an enterprise, especially a business, usually with considerable initiative and risk, women entrepreneurs need to undertake various challenges. This paper identifies and discusses the characteristics, motivations, and obstacles of women entrepreneurs in starting their own businesses, focusing on the Al-Dhahira region of Oman. Data were collected through a structured survey questionnaire. The study identified the major characteristics of women entrepreneurs that inspired them to start their businesses. An urge to balance the work and family life, a search for stable work, and an intention to take advantage of a discovered market niche were identified as main motivators. The major difficulties faced by these entrepreneurs were insufficient financial resources and access to external financing. The findings help explain regional imbalances in entrepreneurial activities locally and globally.