Context: This study aims to examine the extent to which political partisanship— measured as support for the incumbent candidate for Indonesia’s president, Joko Widodo (popularly known as Jokowi) or its former challenger, Prabowo— affects the risk perception of COVID-19 and COVID-19 vaccine hesitancy and refusal as well as beliefs about the safety and efficacy of the COVID-19 vaccine.

Methods: Multinomial logistic and OLS regression analyses on a nationally representative sample of the National Survey on public trust in the COVID-19 vaccines and vaccinations held in December 2020.

Findings: Individuals who voted for Prabowo–Sandi in the 2019 Presidential Election are more likely to have a lower level of willingness and a higher level of hesitancy to get the COVID-19 vaccine than those who cast their ballot for Jokowi–Amin as the Indonesian President.

Conclusions: Political partisanship does matter in shaping individuals’ hesitancy or refusal toward the COVID-19 vaccine in Indonesia. The effect of partisanship is also significant in shaping individuals’ trust in the efficacy and safety of the COVID-19 vaccine, but it is not significantly associated with individuals’ risk perception.

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