The present article seeks to bring together ideas from legal, medical, social science, artistic, and activist perspectives, through dialogue among the four authors. Sarah Creighton is a gynecologist working with women who have atypical genital development or intersex conditions. Julie Greenberg is a professor of law whose work on gender and sexual identity has been influential both within the United States and internationally. Del LaGrace Volcano is a visual artist whose work engages with gender variance. Katrina Roen is an academic who approaches her research on both transgender and intersex from a social science perspective, informed by queer and feminist theorizing. Although the prior work of the four authors clearly indicates a shared commitment to change the situation of intersex people, the mechanisms for such changes are far from clear. Any changes will, however, surely be facilitated by ongoing communication and collaboration across the various perspectives and disciplines represented here.