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drug discovery

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Journal Article
East Asian Science, Technology and Society (1 March 2014) 8 (1): 57–79.
Published: 01 March 2014
... disorders.” 10 The ayurvedic physician leading the drug discovery department in this company told us that this ayurvedic disorder would correspond to polyuria, which includes diabetes (or, according to biomedical nosology, reveals the existence of diabetes). The classical formula used in the treatment of...
Journal Article
East Asian Science, Technology and Society (1 June 2013) 7 (2): 261–281.
Published: 01 June 2013
... study of diabetes. By exploring three planes of the adiponectin research (genetics, epidemiology, and drug discovery), the analysis of this case study suggests that genes and populations, publics and scientists, cardiovascular disease and diabetes are not static objects of medicine but rather interfere...
Journal Article
East Asian Science, Technology and Society (1 March 2013) 7 (1): 7–33.
Published: 01 March 2013
...Masato Fukushima This article analyzes the emergent new discipline known as chemical biology as part of the rapidly developing postgenomic research agenda. Despite chemical biology's academic as well as political significance in terms of its expected contribution to drug discovery, the...
Journal Article
East Asian Science, Technology and Society (1 September 2009) 3 (2-3): 257–285.
Published: 01 September 2009
...Laurence Monnais In the decade between 1935 and 1945, the discovery and diffusion of sulfonamides, commonly known as sulfa drugs, new medicines capable of controlling bacterial infections, launched a true therapeutic revolution. Predating antibiotics, these “first miracle drugs” to quote the title...
Journal Article
East Asian Science, Technology and Society (1 August 2014) 8 (4): 391–415.
Published: 01 August 2014
... information is used to evaluate patent applications for polyherbal drug formulation protection, thus creating a new jurisprudence about the boundaries between the protection and the appropriation of traditional medical knowledge. 14 7 2013 31 3 2014 © Ministry of Science and Technology...
Journal Article
East Asian Science, Technology and Society (1 September 2016) 10 (3): 291–313.
Published: 01 September 2016
... considerations shape the emerging “Hong Kong's bioscience dream.” Using the recent discovery of a new recombinant anticancer drug, pegylated human recombinant arginase (BCT-100), as a case in point, I explore how biotech research and applications are marketed and interpreted in relation to Hong Kong's unique...
Journal Article
East Asian Science, Technology and Society (1 March 2008) 2 (1): 73–92.
Published: 01 March 2008
... laboratory to human experiment is simply a question of mass reproducing and refining results that have already been produced in vitro. As a result, the complexity of drug metabolism appears as nothing more than a hurdle on the road to drug discovery and biomedical innovation—unavoidable but uninteresting in...
Journal Article
East Asian Science, Technology and Society (1 November 2012) 6 (4): 453–464.
Published: 01 November 2012
... theoretical approach based on Gilles Deleuze and Félix Guattari's notion of assemblages, which differs significantly from Latourian actor network theory. The concept's analytic advantages are illustrated by a case study of Taiwan's campaign to stem HIV transmission among injection drug users. It is hoped that...
Journal Article
East Asian Science, Technology and Society (1 March 2012) 6 (1): 101–125.
Published: 01 March 2012
...Timothy Yang This article examines Hoshi Pharmaceuticals' attempt to cultivate cinchona, the raw material for the antimalarial drug quinine, in the mountains of Taiwan during the 1930s and 1940s. Hoshi Hajime, the founder and president of the company, pitched a “humanitarian” vision of quinine self...
Journal Article
East Asian Science, Technology and Society (1 December 2018) 12 (4): 551–554.
Published: 01 December 2018
... common genetic traits. The genetic turn in drug discovery and treatment manifests in two broad ways: in predicting how people with particular genes and their mutations or who are missing them are likely to respond to particular drugs and identifying “ethnic” drugs. Knowing that patients will not...
Journal Article
East Asian Science, Technology and Society (1 September 2011) 5 (3): 313–327.
Published: 01 September 2011
... contracts has served as a means of both formally recognizing limited labor rights and strictly individualizing these rights. 6 As many large multinational pharmaceutical companies have recently set up drug discovery, development, and testing units in China, this means that they are now able to...
Journal Article
East Asian Science, Technology and Society (1 March 2013) 7 (1): 69–85.
Published: 01 March 2013
... major presence in Singapore. GlaxoSmithKline has long manufactured drugs here, and it recently opened a center for research in cognitive and neurodegenerative disorders. Also at Biopolis is the Novartis Institute of Tropical Diseases, focused on drug discovery and vaccines. Singapore is also an...
Journal Article
East Asian Science, Technology and Society (1 August 2014) 8 (4): 417–437.
Published: 01 August 2014
... the shadows of secrecy in which folk practitioners would cloak their medicines and methods. “Secret recipes” ( mifang 秘方) for drug combinations and previously unregistered local botanicals are seen as prime candidates for salvaging, perhaps because as discrete objects they might be relatively easy to...
Journal Article
East Asian Science, Technology and Society (1 September 2013) 7 (3): 425–451.
Published: 01 September 2013
... reformulation of existing drugs, the development of novel preparations, and greater attention being paid to profitability, packaging, branding, and positioning in national and global markets ( Adams 2007 ; Craig 2006 ; Craig and Adams 2008 ). Further transformation followed China's introduction of good...
Journal Article
East Asian Science, Technology and Society (1 March 2016) 10 (1): 5–27.
Published: 01 March 2016
... of the categories of race and ethnicity among scientific articles. This discourse has brought about not only opinions on stricter drug tests for Asian athletes than for athletes of other races but also questioning by Asian athletes of their own selfhood. Ultimately, I show that scholarship exploring...
Journal Article
East Asian Science, Technology and Society (1 March 2017) 11 (1): 127–131.
Published: 01 March 2017
... The discovery of highly active antiretroviral therapy (HAART) in 1995 was effectively a response to the high mortality of AIDS in the global North, where the high cost of industrial pharmaceutical development could be afforded, and where large numbers of researchers could be trained and recruited...
Journal Article
East Asian Science, Technology and Society (1 March 2010) 4 (1): 77–97.
Published: 01 March 2010
..., 2001 [evening ed.]: 16). At the beginning of the twenty-first century, personalized medicine has become the main medical beneficiary of the Human Genome Project ( Nakamura and Nakamura 2001 ), and genome-based drug discovery is also coming on strong ( Emilien et al. 2000 ; Hattori 2005 ). Genomic...
Journal Article
East Asian Science, Technology and Society (1 March 2014) 8 (1): 107–139.
Published: 01 March 2014
... drug development. Here is a somewhat simplistic account explaining why. It is widely recognized today that the most prevalent disorders in societies with advanced economies—diabetes, cardiovascular disease, cancer, depression—have multifactorial causes that, in turn, produce complex pathological...
Journal Article
East Asian Science, Technology and Society (1 March 2017) 11 (1): 107–111.
Published: 01 March 2017
..., Intolerant Bodies pays constant attention to medical treatment and patients’ experience of autoimmune disorders. After the accidental discovery of cortisone as an effective treatment for autoimmune diseases in 1949, and other drugs that suppress immunological reactivity in the following years, it became...
Journal Article
East Asian Science, Technology and Society (1 September 2016) 10 (3): 315–319.
Published: 01 September 2016
... project: cross-cultural in character, with well-known complexity. A theoretical framework grounded in recent biological, climatological, and psychological discoveries, as well as Dux's “historical-genetic theory of culture,” thus underlies the contributions, all of which aim to evaluate the varying...