The introduction argues for an interspecies relational ethic premised on indifference to the difference of others—that is, premised on mutual regard rather than curiosity, love, or animus. The introduction begins with a review of the role curiosity plays in interspecies scholarship and moves toward an ethos of opacity, or mutual regard. It surveys a path toward a commitment to animal ethics, tracing the role of caste, patriarchy, and queerness. The introduction concludes with a brief map of the book and each chapter's relation to the concept of indifference.